概述
In 1997, the American Urological Association (AUA) published the Guideline on the
Management of Primary Vesicoureteral Reflux in Children.1
Since that time there has been an
expanding body of literature involving not only the evaluation and the management of
vesicoureteral reflux (VUR) but also the role of screening in its management. For this reason, the
AUA appointed a Panel of experts to update the 1997 document and elected to expand its scope
to include guidelines for the screening of siblings of children with vesicoureteral reflux (VUR)
and of neonates/infants with prenatally diagnosed hydronephrosis. A literature search, review of
the evidence, and data extraction from the relevant clinical studies and case series were
performed. Extracted data underwent meta-analysis to determine the outcomes related to five
topics: 1) management of children over one year of age with VUR; 2) evaluation and
management of infants with VUR; 3) management of children with VUR and Bladder and Bowel
Dysfunction (BBD); 4) screening of siblings and offspring of patients with VUR; and 5)
screening of neonates and infants with prenatal hydronephrosis. This document summarizes the
guideline statements derived from a meta-analysis. Additional chapters (1-5) provide a detailed
summary of each of these topics.
