概述
Syphilis is a complex, cutaneous and multi-system disease caused by the spirochete Treponema palladium. Syphilis is transmitted sexually, congenitally, and through blood products. It can involve nearly every organ system. Its clinical course involves several well-characterized stages: an incubation period, a primary stage, a secondary stage, a latent stage, and a late or tertiary stage .
The present guidelines aim to provide comprehensive information onsyphilis, including epidemiology, clinical features, diagnosis, and management. The guidelines provide evidence-based recommendations on the prevention and treatment of syphilis in adults in Asia, including special populations like pregnant females and patients with HIV coinfection. In these guidelines, March 2009 Oxford Centre for EvidenceBased Medicine’s Levels of Evidence have been used to classify the level of evidence of various assertions and recommendations.